PSM
Luis Felipe Falla-Zuniga, MD (he/him/his)
Research Fellow
Mercy Medical Center
Baltimore, Maryland, United States
Luis Felipe Falla-Zuniga, MD (he/him/his)
Research Fellow
Mercy Medical Center
Baltimore, Maryland, United States
Mary Caitlin King, BS
Clinical Research Supervisor
Mercy Medical Center, United States
Kathleen Pawlikowski, BA
Research Coordinator
Mercy Medical Center, United States
Vladislav Kovalik, MD (he/him/his)
Research Fellow
Mercy Medical Center, Maryland, United States
Felipe Lopez-Ramirez, MD (he/him/his)
Research Fellow
The Institute for Cancer Care, Mercy Medical Center
Baltimore, Maryland, United States
Philipp Barakat, MD
Research Fellow
The Institute for Cancer Care, Mercy Medical Center, United States
Andrei Nikiforchin, MD (he/him/his)
Research Fellow
Mercy Medical Center
Baltimore, Maryland, United States
Sergei Iugai, MD (he/him/his)
Research Fellow
Mercy Medical Center
Baltimore, Maryland, United States
Carol Nieroda, MD
Research Advisor
Mercy Medical Center, United States
Vadim Gushchin, MD, FACS
Director, HIPEC Program at Mercy
Mercy Medical Center, Maryland, United States
Armando Sardi, MD, FACS (he/him/his)
Medical Director
The Institute for Cancer Care, Mercy Medical Center
Baltimore, Maryland, United States
Armando Sardi, MD, FACS (he/him/his)
Medical Director
The Institute for Cancer Care, Mercy Medical Center
Baltimore, Maryland, United States
Overall, 157/471 (33.3%) survivors completed the questionnaires. Median age was 62 (IQR: 52-68) years, 82.3% (n=130) were white, 69.4% (n=109) were married, and 49.0% (n=77) were employed. Median time from diagnosis was 66 (IQR: 33-120) months. Primary tumor type included appendix (n=96), ovarian (n=38), colon (n=12), and other (n=11). Median FACT-G total score was 91 (IQR: 77-100) with 20.4% (n=32) reporting a low QoL. Overall QoL was negatively associated with comorbidities (p< 0.01), painkiller use (p< 0.01), recurrence after last treatment (p=0.02), and active cancer treatment (p=0.01). Four (Figure 1) and 10 questions of the post-CRS/HIPEC QoL questionnaire were strongly and moderately associated with overall QoL, respectively. Internal consistency between the 14 questions was excellent (Cronbach’s alpha=0.9). Attitude towards CRS/HIPEC was positive in 90.4% (n=142) of participants.
Conclusions:
Although a high proportion of CRS/HIPEC survivors reported a high QoL, they still faced issues not captured in a standard QoL questionnaire. Development of QoL assessments tailored to the unique CRS/HIPEC experience can provide a better picture of life after CRS/HIPEC, improve program development, and aid survivorship. Prospective and early postoperative evaluation of this post-CRS/HIPEC QoL questionnaire is needed.