E104: Surgical outcomes and SHORT-TERM survival analyses of patients with Signet ring cell colorectal carcinoma

Introduction: Primary signet ring cell colorectal carcinoma (PSRCCR) is a rare entity with a dismal prognosis, mainly because of delayed diagnosis.

Methods:

Methods: Data of 32 patients with Primary signet ring cell colorectal carcinoma (PSRCCR) who underwent surgery from January 2013-December 2018 was retrieved from our data base. Patients were categorized by age, sex, tumor site, and stage.

Results: Of 32 patients ,27 patients were male, 5 patients were female. Median age was 37 years. Sites for metastases were lymph nodes (9.5%), peritoneum (19%), and Others (12.5%). Locoregional recurrence occurred in (6.2%). Most of the patients (93.75%) had stage III tumors.

Conclusions:

Conclusion: It was concluded that site of the tumor, presence of bowel obstruction, peritoneum and lung metastases, adjacent organ infiltration, TNM stage, and efficiency of surgery have significant effects on survival. All in all, these aggressive tumors are generally diagnosed at advanced stages. Depending on the situation, survival is shorter. A high degree of vigilance is required for these patients to avoid the negative impact of late diagnosis on survival.
Keywords: Signet-ring cell; Adenocarcinoma; Colorectum; Prognosis; Stage